Fibromyalgia Clinical Trial Targeting Herpes Virus

fibromyalgia clinical trial antiviralBack in September of last year, Dr. Pridgen was in the news saying he believes Fibromyalgia , other chronic pain conditions, chronic fatigue, and Gastrointestinal disorders are caused by the herpes simplex virus, the virus best known for causing cold sores.  There wasn’t much of a ruckus made about this, and rightly so, considering the scores of ME/CFS and fibromyalgia patients that have taken acyclovir, valtrex, valcyte, to no avail.

But something caught my eye.  By hitting the virus in 3 different stages of the viral life cycle, 90% of his patients responded to his therapy.  Jaded me to the wind, I looked forward to the study.

This trial is now officially recruiting: http://clinicaltrials.gov/ct2/show/NCT01850420?term=%22fibromyalgia%22+%22hsv%22&rank=1  Although it’s not listed on clinicaltrials.gov, Dr. Pridgen said in a separate announcement that he was throwing in a NSAID medication.  In fact the drug cocktail is property of the company co-founded by Pridgen, so none of the drug names are publicized.  This makes it difficult for busybodies like myself to speculate.

Personally I find the addition of a NSAID to the fray a lot more interesting than yet another standalone antiviral.  As the momentum in ME/CFS and fibromyalgia circles shifts more toward “autoimmune with a virus”, I hope to expect to see a lot more clinical trials designed like this.

  • rrrr

    thanks for posting about this!

  • rrrr

    Above is the clinical trial website on clinicaltrials.gov, and here is the NCT code to help potential research subjects find more information about the research study: The NCT code is NCT01850420, and by typing this number into the search field, it will take them to the page where they will find items such as:

    1. The study locations where subjects are being recruited. Currently there are 12 active sites, all in the US.
    2. That the study drug is investigational and there is a placebo arm. Patients need to be aware that they may not receive the investigational drug.
    3. Important Exclusion Criteria such as history of rheumatologic diseases, bipolar disease, OCD, severe anxiety, schizophrenia, systemic infection, severe cardiac disease, chronic steroid usage, and chronic opioid usage will not be eligible.

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